Unless a wound is correctly treated using Medicine within an hour of the wound being received, the wound may become infected. Treating a wound involves cleaning it and (if necessary) bandaging it to prevent dirt entering the wound subsequently The medic must make a dice roll using his/her CO + Medicine (including First Aid specialism). A successful result means that the wound will not become infected and also gives the wounded character a bonus on his/her dice roll to avoid Shock. Only one attempt to treat a wound is allowed. The basic difficulty of the dice roll depends on the severity of the wound:
| Wound severity | Difficulty |
| Scratch | 0 |
| Light | 2 |
| Medium | 4 |
| Serious | 6 |
| Critical | 8 |
If a wound was not correctly treated within one hour of being received, there is a chance that it will become infected. Also, if a treated wound is subsequently exposed to dirt, there is a chance that it will become infected. In either case an infection check must be made at the end of the day (if the wound has not been magically healed in the meantime).
To make an infection check, roll 2D and consult the following table to see whether the wound becomes infected:
| Climate | Basic chance of infection |
| Tropical rainforest or swamp (Hot/damp) | 5 or less |
| Desert (Hot/arid) | 3 or less |
| Woods (Temperate/damp) | 3 or less |
| Plains (Temperate/dry) | 2 or less |
| Tundra (Cold) | 1 or less |
| Situation | Increase to chance of infection |
| Scratch | +0 |
| Light wound | +1 |
| Medium wound | +2 |
| Serious wound | +3 |
| Critical wound | +4 |
| Wound was dirty (e.g. animal bite, weapon covered in animal dung, etc.) | +2 |
| Wound was poisoned with a blood agent | +4 |
Each week, an infected wound will progressively get worse (e.g. a Light wound becomes a Medium wound, a Critical wound causes death), until it is successfully treated using Medicine or cured magically. If an infected wound becomes Fatal, the character dies.
To treat an infected wound, a medic must make a dice roll using his/her PE + Medicine (including Treating infection specialism). A successful result means that the wound is no longer infected. One attempt to treat an infected wound is allowed per week. The difficulty of the dice roll depends on the current severity of the infected wound:
| Wound severity | Difficulty |
| Scratch | 1 |
| Light | 3 |
| Medium | 5 |
| Serious | 7 |
| Critical | 9 |
There is a bonus of +2 on the dice roll if the infected character has rested for the week.
See also: example of a wound